Blog > Effectiveness of Sildenafil Citrate Induced Medicines to Treat Erectile Dysfunction
Effectiveness of Sildenafil Citrate Induced Medicines to Treat Erectile Dysfunction

Effectiveness of Sildenafil Citrate Induced Medicines to Treat Erectile Dysfunction

by | Jul 31, 2025 | Erectile Dysfunction

Sexual Disorders often stay undiagnosed due to societal taboos, misunderstanding and other health complexities. Disorders like Erectile Dysfunction (ED) affect millions of men worldwide and impose difficulties on sexual health. To effectively treat ED, medical involvement is also prominent. One such medicinal composition is Sildenafil Citrate. 

At Global Care Meds, we offer our customers premium-quality ED medications containing Sildenafil Citrate. You may have doubts, such as how long Sildenafil lasts or how effective it is. We have prepared this blog to address your common questions and provide you with a comprehensive guide. Continue reading to know more. 

Symptoms of Erectile Dysfunction 

Not all failures in a sexual performance are a sign of Erectile Dysfunction. Sometimes, due to physical, social and psychological conditions, men might fail to obtain a firm erection and retain it for a longer timeframe. These are rare incidents and are not considered ED. However, if it lasts for a longer timeframe and imposes other symptoms as well, it might indicate the occurrence of ED. 

The following are the main symptoms of erectile dysfunction: 

  • Having trouble with erection even after sexual stimulation. 
  • Difficulty in maintaining an erection during sexual intercourse. 
  • Premature Ejaculation 

Apart from the above-mentioned side effects related explicitly to ED, the following symptoms can also occur: 

  • Lower level of libido 
  • Low interest in sexual intercourse 
  • Shame and Embarrassment 
  • Low Self-Esteem 
  • Stress and Anxiety 

What is Sildenafil Citrate? 

Sildenafil Citrate is a medication that is designed to treat sexual disorders in men like Erectile Dysfunction (ED). This medicine works by incresaing the blood flow to the penis, making it easier to maintain an erection while being sexually aroused. 

An enzyme called phosphodiesterase type 5 (PDE-5), present in the body, restricts blood flow to the penis. As a result, during sexual intercourse, the penis fails to expand and stay erect for effective performance. This condition is called ED. 

Sildenafil Citrate is a PDE-5 inhibitor that blocks the enzyme. By inhibiting the enzyme, blood flow to the penis is restored. During sexual arousal, proper blood flow helps it to expand and stay erect for a more extended period and perform the climax accordingly. 

Popularly used ED Medicines like Cenforce 100 mg tablets, alongside related doses of Cenforce 130 mg and 150 mg tablets, contain Sildenafil Citrate to work accordingly. 

How long does Sildenafil Citrate take to Work? 

Sildenafil doesn’t cause a spontaneous erection, but it enhances your natural response to sexual stimulation. This can allow a more satisfying experience during sexual intercourse. Only taking this medicine will not give an erection. You would need to have adequate sexual stimulation along with this medicine to get a firm erection and retain it for a more extended period to have better sexual performance. 

For instance, medicines such as Begma 100 mg tablets and their higher doses, 120 mg and 200 mg tablets, are highly effective alternatives to sildenafil citrate. Medical research has confirmed that Sildenafil Citrate takes approximately 30 to 60 minutes to start working. In some men, it takes approximately 1 hour to reach peak effectiveness after taking the medication. Whereas, for some men, it takes approximately 12 to 15 minutes to get an erection after taking the medicine. However, multiple lifestyle differences can restrict or reduce the effectiveness of Sildenafil Citrate. The full effects of a medicine can be delayed, depending on what you have eaten. 

For instance, medicines such as Cobra 120 mg tablets may take up to 1 hour for their effects to take place. Hence, doctors might prescribe men to take this medicine 1 hour before sexual intercourse and wait for at least 5 to 10 minutes for proper functioning. 

How long does Sildenafil Citrate last? 

Just as the appropriate timeframe for Sildenafil Citrate to start working is not determined, the lasting impact is also uncertain. The effect of sildenafil citrate may last between 4 and 6 hours. During this time, you will be able to achieve and maintain an erection if you are sexually aroused. 

For instance, medicines like Extra Super P Force Tablet and Femafil 100 mg tablets might last upto 6 hours.  However, other drugs such as Filagra Double 200 mg Tablets and their other doses, such as Filagra DXT Plus, might last upto approximately 3.5 to 4 hours. This duration may vary depending mainly on the physical condition and severity of the situation, as well as other psychosocial factors. 

Duration of Sildenafil’s effects may vary depending mainly on the following factors: 

  • Metabolism

Individuals with higher metabolism can process drugs more quickly. In some instances, the effect of Sildenafil Citrate might wear off quickly. Whereas, for individuals with lower metabolism, the medicinal effect might last longer.  

  • Dosage  

Sildenafil citrate is available in various dosage forms. For instance, medicines such as Fildena 50 mg tablets might be less effective than doses like Fildena Professional 100 mg tablets. Your doctor will prescribe the correct dose based on the severity of your condition and your specific needs for the medication. 

Best Time to Take Sildenafil Citrate Medicines 

Most men are advised to take medicines containing Sildenafil Citrate at least 1 hour before sexual intercourse. Medical research has confirmed that it might take at least 30 minutes to take effect and last up to 4 hours. However, the timeframe might vary depending on the effectiveness of the medicine dose and the severity of the condition. 

In case of medicines like Kamagra 100 mg chewable tablets, having heavy meals beforehand can delay how quickly the drugs enter the bloodstream. Hence, doctors often recommend taking Sildenafil tablets on an empty stomach. On the other hand, medical research has confirmed that food doesn’t make the medicine any less effective; however, it may be more effective when taken on an empty stomach. 

Comparison with other ED medicines 

Sildenafil Citrate is used for erectile dysfunction is a popular option used to treat Erectile Dysfunction (ED). Here’s a quick comparison between  medicines containing sildenafil and other compositions: 

Tadalafil vs. Sildenafil 

Tadalafil is a PDE-5 Inhibitor just like Sildenafil. In some instances, Tadalafil may start working 15 minutes after taking it, whereas Sildenafil may take 30 minutes. However, the duration of action for Tadalafil may be shorter by 1 to 2 hours than that of Sildenafil. These aspects vary depending on multiple physical, social and emotional factors. Longer impact imposed by medicines like Ladygra 100 mg tablets makes it even more preferable among men and women with sexual disorders. 

Avanafil vs. Sildenafil 

Avanafil is another PDE-5 inhibitor, similar to sildenafil. However, the faster-acting capability of Avanafil, which takes effect within 18 to 20 minutes, makes it a more popular choice among affected men compared to Sildenafil. The retention ability of avanafil is also upto 6 hours, the same timeframe you can expect for sildenafil. 

For instance, medicines like Malegra 50 mg tablets and associated doses involving Malegra DXT Plus, Malegra FXT Plus, Malegra Green 100 mg tablets, and Malegra Oral Jelly are often more effective than those under Avanafil. It is better to receive a thorough doctor’s consultation regarding the specific effectiveness of which medicine might help you. 

Vardenafil vs. Sildenafil 

Similar to Sildenafil tablets, Vardenafil is also a PDE-5 inhibitor, which might start to work 30 to 60 minutes after consumption. However, the duration of action of Vardenafil may be 2 hours, compared to 4 hours for Sildenafil Citrate. Hence, medicines like Manforce 100 mg tablets containing Sildenafil are popularly used for retaining an erection during sexual intercourse. 

Precautions to be taken 

Erectile Dysfunction (ED) is a complex disorder, and faulty medicine consumption can result in further adverse health impacts. For instance, medicines like Silagra 100 mg tablets might impose side effects such as headache, diarrhea, dizziness, stomach upset and muscle pain. To prevent such symptoms, you can take the following precautions: 

  • Contact your healthcare professional immediately if any side effects occur.
  • Check the medicine’s instructions properly and follow them accordingly.
  • Drink adequate water and keep your body hydrated
  • Keep your blood pressure in check
  • Avoid alcohol and specific fruit juice consumption while being on the medicine.
  • Don’t panic; Rest and relax.
  • Consult your doctor if you have any questions or concerns.

Conclusion 

Erectile Dysfunction is a complex condition, but with the right medicine, you can control the symptoms and gradually cure the complexities. At Global Care Meds, we offer FDA-approved medications to treat erectile dysfunction and related conditions. Owing to the wide demand for medicines containing Sildenafil Citrate, we offer a curated list that is suited to treat complex issues of erectile dysfunction. Connect with us today for the best-quality ED medicines.

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